OSAKA UNIV. CBCMP

OSAKA UNIVERSITY CHEMISTRY - BIOLOGY COMBINED MAJOR PROGRAM

Chemistry Biology Experiments 2

Outline

The Chemistry portion of LABX-225 (“Chemistry Biology Experiments 2″) focuses on experimental Organic Synthesis, and follows on from LABX-215, the chemistry portion of which concentrates on practical analytical techniques.

 

Classes are held over 5 to 6-hour sessions, and roughly alternate weekly with the equivalent Biology experimental portion of LABX-225.

Learning outcomes

 

Students will build on the basic organic synthetic techniques they learned in their previous years.  Students will learn how to:

  conduct a variety of common work-up techniques;

  conduct reactions that are water sensitive (e.g. Grignard) by using nitrogen as a blanket gas;

  conduct reactions that are air sensitive (e.g. Suzuki-Miyaura) by using Schlenck line techniques;

  characterise reaction products through the full range of standard techniques (including m.p.; IR; 1H NMR);

  and work independently, so they will be able to both synthesise and characterise a simple compound without intervention from teaching staff.

Textbook

LABX-225 Chemistry & Biology Experiments 2 – Laboratory Manual (Chemistry), Osaka University International College, 2015.

 

 

This lab manual will be provided in paper form in the first (orientation) class, and in electronic form before that.

No Photo

Syllabus

 2015 syllabus and timetable still under construction….

 

(The 2014 course featured the following experiments:

  Basic Organic Work-up Techniques

  Wittig Reaction

  Feidel-Crafts + Aldol Reactions

  Grignard + Nucleophilic Cu(I) Reactions

  RAFT polymerization of styrene

  Suzuki-Miyaura cross-coupling polymerization

  Final examination: Sn2 reaction)

 

Grading

 

Grading is as follows:

 

  Laboratory reports:             60%    (4 x 15 %)

  Laboratory performance:     20%

  Final practical examination:  20%

 

Laboratory performance covers such things as:
   Are you adequately prepared for each class?
   How you interact in class:
        Do you ask questions?
        Are you an active or passive participant?
   Do you follow safety procedures properly?
   The contents of your lab book

Instructor

Associate Professor

Luke Ueda-Sarson

Luke Dylan Ueda-Sarson